Effective Dosage: There is currently no clinical evidence that Melatonin is effective as a weight loss supplement at any dosage.
Melatonin is a hormone produced by the pineal gland that mediates circadian rhythms and other physiological functions. Melatonin synthesis and secretion decrease significantly by middle age and this decline is associated with the increase in visceral adiposity that occur with aging, especially in men.
In a 12-week rodent study, rats given melatonin experienced reductions in body weight, visceral fat, plasma leptin and plasma insulin levels. However, the effects of daily melatonin administration on energy balance in humans have not been determined.
These statements about Melatonin have not been evaluated by the Food and Drug Administration. Melatonin is not intended to diagnose, treat, cure, or prevent any disease.
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