Effective Dosage: There is currently no clinical evidence that L-ornithine is effective as a weight loss supplement at any dosage.
L-ornithine is a basic amino acid and is important in the formation of urea. It is a nonprotein amino acid which means that it does not occur in proteins. The body uses it in the biosynthesis of L-arginine, L-proline and polyamines.
L-ornithine is sometimes used as a nutritional supplement for its anabolic activity, even though there is little evidence to support this. However, there is a derivative of L-ornithine called ornithine alpha-ketoglutarate or OKG which, under certain conditions, may have immunomodulatory and anticatabolic and/or anabolic actions.
Animal research has suggested that L-ornithine, along with arginine, may promote muscle-building activity in the body by increasing levels of anabolic (growth-promoting) hormones such as insulin and growth hormone. L-ornithine is also said to increase the metabolism of fat. There have been no clinical human studies conducted that support these claims.
These statements about L-ornithine have not been evaluated by the Food and Drug Administration. L-ornithine is not intended to diagnose, treat, cure, or prevent any disease.
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